2020 Medicinal Chemistry Reviews

Volume 55, Chapter 13
Recent Progress in the Discovery and Clinical Application of Small-Molecule Inhibitors EZH2 and EED
Julian R. Levell

1. Introduction
2. Recent Advances in the Discovery of Small-Molecule Catalytic Inhibitors of EZH2
3. EED Ligands
4. Other Modes of Targeting EZH2 and/or EED
5. Clinical Compounds
6. Conclusions

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ACS Division of Medicinal Chemistry

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