2019 Medicinal Chemistry Reviews

Volume 54, Chapter 16
Design and Tactical Applications of Prodrugs to Enable Effective Drug Delivery
Murugaiah A. M. Subbaiah, Nicholas A. Meanwell

1. Introduction
2. Solubility-Enhancing Prodrugs
3. Permeability-Enhancing Prodrugs
4. Transporter-Targeted Prodrugs
5. Site-Specific Prodrugs
6. Sustained Release Prodrugs
7. Other Prodrugs
8. Conclusion

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ACS Division of Medicinal Chemistry

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