2019 Medicinal Chemistry Reviews

Volume 54, Chapter 6
Untangling Perception and Reality: Small-Molecule TNF-α Inhibitors
Jeremy J. Edmunds

1. Introduction
2. Design of Small Molecules Disrupting the TNF-α Trimer
3. Design of Small Molecules Inhibiting TNF Transmembrane Type 1 and Type 2 Receptors
4. Conclusions

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ACS Division of Medicinal Chemistry

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