2018 Medicinal Chemistry Reviews

Volume 53, Chapter 2

A Journey in Cardiovascular Drug Discovery:  New Frontiers and Lessons Learned

Ruth Wexler

1.  The Early Years                      17

2.  DuPont: The Angiotensin II Era (1982-1991)    18

3.  A Focus on Antithrombotics: Discovery of Apixaban (1991-2001)  21

4.  Bristol-Myers Squibb: Cardiovascular Drug Discovery (2001-present)    26

5.  My Reflections: The Past, the Present, and the Future                          31

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