Medicinal Chemistry Reviews

Volume 52, Chapter 4

Advances and Insights from CNS G Protein-Coupled Receptor Crystallography

1.          Introduction                                                                                                               69

2.         Overview of GPCR Structural Biology Approaches                                                 72

3.         Overview of Orthosteric Structures of CNS GPCRs                                                 74

4.         Allosteric Modulation of CNS GPCR Targets                                                           80

5.         Conclusions              

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