Medicinal Chemistry Reviews

Volume 50, Chapter 9
Targeting the B-Cell Receptor Pathway in Hematological Malignancies
Kevin S. Currie

1.    Introduction                                                                                                            225         

2.   Btk Inhibitors                                                                                                              227

      2.1        Covalent Inhibitors                                                                                         227

      2.2       Non-covalent Inhibitors                                                                                 229

3.   PI3Kδ Inhibitors                                                                                                          230

4.   Syk Inhibitors                                                                                                              232

5.   Conclusions                                                                                                                 234

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