Medicinal Chemistry Reviews

Volume 50, Chapter 1
Science, Art, and Drug Discovery:  A Personal Perspective
Sir Simon F. Campbell

1.    The Formative Years                                                                                                   17

2.   α1-Adrenoceptor Antagonists and Doxazosin                                                         19

3.   Calcium Antagonists and Amlodipine                                                                      22

4.   PDE5 Inhibitors and Sildenafil                                                                                  24

5.   Some Additional Thoughts on Drug Discovery                                                        26

6.   Conclusion                                                                                                                   27

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